SAMe 200

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

ProThera, Inc.

200 mg Elemental SAMe s-adenosyl l-methionine

Dietary Supplement

Suggested use: 1 to 6 tablets daily on an empty stomach.

Warning: Individuals being treated for neurological conditions, including those using prescribed medications such as antidepressants, serotonin reuptake inhibitors, and MAO inhibitors, should consult their healthcare professional before using this product. Individuals with bipolar disorder or manic depression should not take SAMe unless under medical supervision.

Warning: Individuals being treated for neurological conditions, including those using prescribed medications such as antidepressants, serotonin reuptake inhibitors, and MAO inhibitors, should consult their healthcare professional before using this product.

Free of the following common allergens: milk/casein, egg, fish, shellfish, tree nuts, peanuts, wheat/gluten, and soybeans.

ProThera's SAMe 200 is provided in individual foil blister-packets to maximize product stability.

Do not use if outer seal of blister pack is broken.

Store in a cool, dry place (59(0)F-85(0)F) away from direct light.

Keep out of reach of children.

SAM rev100112A

Made in Italy

ProThera provides pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions. An enteric tablet coating resistant to gastric acidity helps to further ensure a biologically active product.

Each tablet contains a full 200 mg of elemental SAMe from 400 mg SAMe tosylate disulfate.

SAMe (S-Adenosylmethionine) is a derivative of the essential amino acid methionine and is formed by combining ATP with methionine.

SAMe has a long history of clinical use with proven benefits for brain metabolism, joint function, and liver detoxification. Some of the reported beneficial actions of SAMe include: Joint and connective tissue strength SAMe supports production of healthy connective tissue and joint structures by contributing its sulfur component for transulfuration processes that help form glucosamine and chondroitin sulfates, critical components of connective tissues. Brain metabolism SAMe serves as a major source of methyl groups used by the brain in the synthesis of neurotransmitters such as serotonin, L-dopa, dopamine, and related hormones involved in mood regulation. Liver function Metabolism of SAMe supports synthesis of glutathione and glutathione-dependant enzymes (glutathione peroxidase and glutathione-S-transferase), which are important antioxidants used in liver detoxification processes.