Huperzine A

Category: non-nutrient/non-botanical

Group: Huperzine

Huperzine A is a natural alkaloid compound extracted primarily from the Chinese club moss Huperzia serrata. It acts as a potent, reversible acetylcholinesterase inhibitor, which helps increase acetylcholine levels in the brain, supporting cognitive function and memory.

Also known as:

Memorzine™MossChinese MossToothed Clubmoss aerial parts extractHuperzia serrata aerial parts extract

UNII Code: 0111871I23

Disclaimer: The information below is AI-generated analysis and should not be considered medical advice. Data may be incorrect, incomplete, or outdated. We are not responsible for the quality, accuracy, or reliability of this information. Always consult your healthcare provider before using any ingredients or products.

Uses

Huperzine A is used to improve memory, cognitive function, and mental alertness. It may help slow cognitive decline in neurodegenerative diseases by inhibiting the breakdown of acetylcholine, a neurotransmitter important for learning and memory. It is also used in nootropic formulations to support brain health and mental performance.

Common Uses:

Cognitive SupportMemory EnhancementNootropicNeuroprotection

Side Effects

Huperzine A is generally well tolerated at recommended doses but may cause side effects such as nausea, diarrhea, sweating, blurred vision, muscle twitching, and restlessness in some individuals.

Common Side Effects:

NauseaDiarrheaSweatingBlurred visionMuscle twitchingRestlessness

Rare Side Effects:

Bradycardia (slow heart rate)Severe muscle crampsFainting

Precautions

Use with caution in individuals with heart conditions, epilepsy, or asthma. Avoid use during pregnancy and breastfeeding due to insufficient safety data. Consult a healthcare professional before use if taking medications or if you have underlying health conditions.

Avoid if:

Pregnant womenNursing mothersIndividuals with epilepsyIndividuals with heart conditions

Consult healthcare provider if:

People taking cholinergic or anticholinergic medicationsIndividuals with asthmaPeople with cardiovascular diseaseThose on prescription medications

Drug Interactions

Huperzine A may interact with cholinergic drugs, acetylcholinesterase inhibitors, anticholinergic medications, and drugs affecting the parasympathetic nervous system. It may potentiate the effects of other cognitive enhancers and increase the risk of side effects.

Medications that may interact:

DonepezilRivastigmineGalantamineAnticholinergic drugsCholinergic agents

Dosing

Typical dosing ranges from 50 to 200 micrograms (0.05 to 0.2 mg) per day, often divided into one or two doses. It is recommended to start at the lower end of the dosing range to assess tolerance. Consult a healthcare professional for personalized dosing.

Typical range:0.05mg - 0.2mg

Times per day:1 to 2 times daily

Best taken:Best taken with meals to reduce potential gastrointestinal discomfort